Administration by Injection

Mouse

Injection Routes and Volume

• Intravenous (maximum volume = 0.2 ml)
• Intraperitoneal (maximum volume = 2-3 ml)
• Subcutaneous (maximum volume = 2-3 ml)
• Intramuscular (maximum volume = 0.05 ml)
• Intradermal injections are difficult in mice and are therefore not recommended (maximum volume =0.01 ml)

Rat

Injection Routes and Volume

• Intravenous (maximum volume = 0.5 ml)
• Intraperitoneal (maximum volume = 5-10 ml)
• Subcutaneous (maximum volume = 5-10 ml)
• Intramuscular (maximum volume = 0.3 ml)
• Intradermal (maximum volume =0.05 ml)