Pediatric Cancer Research Foundation (PCRF) Grants

Sponsor Name: 
Pediatric Cancer Research Foundation
Description of the Award: 

The Pediatric Cancer Research Foundation (PCRF) identifies and invests in leading edge research that demonstrates the best hope for a cure to childhood cancer. PCRF is a pioneer in eliminating childhood cancer through our ability to identify and fund cutting edge research. PCRF exclusively targets funds toward emerging and breakthrough opportunities.

Three grant opportunities currently exist:

  • Basic Research Science Grant (up to $250,000 per year, for up to three years)
    • These grants fund basic science, translational and/or clinical state of the art pediatric cancer research initiatives. These grants fund work that is the basis for childhood cancer research, helping to move science in the direction of improved treatments and eventually finding a cure. They are designed to move hypothesis-driven research into the clinic providing support for important preclinical projects that are necessary to move a study from the pre-clinical arena into a clinical trial. Applicants must be a PhD (with a least two years as a junior faculty or assistant professor) and/or MD.

  • Translational Research Grant (up to $100,000 per year, for up to two years)
    • These grants fund new research protocols and therapies that hold promise for improved outcomes and accelerates cures from the laboratory bench to the bedside of children and teens with high-risk cancers. This Grant is given to single or multi-institutional programs that involve open, cancer clinical trials or consortia, and implement new approaches to therapy. Applicants must be a PhD and/or MD.

  • Emerging Investigator Fellowship (up to $50,000 per year for one year)
    • These grants are designed to support Post-Doctoral Fellowships and Clinical Investigator training for emerging pediatric cancer researchers to pursue exciting research ideas. Applicants must have completed two years of their fellowship or not more than two years as a junior faculty instructor or assistant professor at the start of the award period. These grants encourage and cultivate the best and brightest researchers of the future.

Policies and procedures

  • PCRF requires the submission of a Letter of Intent (LOI) through Proposal Central. An institution may only submit one LOI per award type. Multiple LOIs should not be submitted by the same researcher.
  • Researchers not previously funded by the foundation are typically funded at the Emerging Investigator Fellowship level.
  • Selected researchers will be invited to submit a grant application via Proposal Central. The applications deadline is May 31st.

More informaton about PCRF can be found at

PCRF Grant Criteria and Eligibility

  • The probability of an advance in prevention, diagnosis or treatment for the near-term
  • The novelty of the concept and strategy
  • The clarity of presentation
  • The overall plan for bringing the research findings to clinical application
  • Experience, background, and qualifications of the investigators
  • Adequacy of resources and environment (facilities, patients, etc.)
  • PCRF does not have citizenship requirements for our investigators. However, the Principal Investigator needs to be employed by a non-profit U.S. institution that has an affiliation with a hospital.
  • Basic Science Research and Translational Grants require the applicant to be a PhD and/or MD.
  • Emerging Investigator applicants must have completed two years of their fellowship, or not more than two years as a junior faculty instructor or assistant professor at the start of the award period.

PCRF limits on Letters of Intent to one LOI per available award type (Basic Science Research, Translational Research, Emerging Investigator Fellowship).

Sponsor Final Deadline: 
Mar 01, 2023
OSVPR Application or NOI Instructions: 

Interested applicants should upload the following documents in sequence in one PDF file (File name: Last name_PCRF_2023) no later than 4:00 p.m. on the internal submission deadline:

  1. Cover Letter (1 page, pdf):
    1. Descriptive title of proposed activity
    2. PI name, departmental affiliations(s) and contact information
    3. Title of this funding opportunity
  2. Research project (limit 3 pages) addressing the following questions:
    1. How does this proposal fit the goals and objectives of PCRF?
    2. What need/issue are you addressing?
    3. Why is your approach novel?
    4. What outcomes do you hope to achieve?
    5. Why are you and your institution the best equipped to carry out this activity?
  3. References
  4. NIH Biosketches (limit 5 pages)

Formatting Guidelines:

Font/size: Times New Roman (12 pt.)
Document margins: 1.0” (top, bottom, left and right)
Standard paper size (8 ½” x 11)

To be considered as a Penn State institutional nominee, please submit a notice of intent by the date provided directly below.
OSVPR Downselect Deadline: 
Thursday, February 2, 2023 - 4:00pm
For help or questions: 

Penn State College of Medicine applicants should please contact Jess Kiely, Director of Corporate and Foundation Relations, ( for additional support. University Park applicants for Basic Science Grants should please contact Andrew Kuhn, Assistant Director, Foundation Relations ( for additional support.