(CLOSED) NIH RFA-NS-19-024 HEAL Initiative: Early Phase Pain Investigation Clinical Network - Data Coordinating Center (U24 Clinical Trials Not Allowed)

Sponsor Name: 
NIH
Amount: 
$5,400,000.00
Description of the Award: 

The purpose of this funding opportunity announcement (FOA) is to invite applications for the Data Coordinating Center (DCC) of the Early Phase Pain Investigation Clinical Network (EPPIC-Net). EPPIC-Net will serve as the cornerstone of the NIH’s Helping to End Addiction Long-term (HEAL) Partnership. EPPIC-Net will provide a robust and readily accessible infrastructure for carrying out in-depth phenotyping and biomarker studies in patients with specific pain conditions, and the rapid design and performance of high-quality Phase 2 clinical trials to test promising novel therapeutics for pain from partners in academia or industry. Studies will bring intense focus to patients with well-defined pain conditions and high unmet therapeutic needs.

EPPIC-Net will consist of one Clinical Coordinating Center (CCC), one Data Coordinating Center (DCC) and approximately 10 specialized clinical centers (“hubs”). As the main data manager for pain research in the HEAL Initiative, the EPPIC-Net DCC will host and manage clinical, neuroimaging, biomarker, omics, and preclinical data from EPPIC-Net and other components of the HEAL Initiative’s pain research program. The DCC will also make these data and clinical biosamples available to the research community to advance the science of pain. Lastly, the DCC will provide leadership in the statistical design and analysis of EPPIC-Net studies, and the systems and processes for data collection, management, quality assurance and reporting.

This FOA solicits applications for the EPPIC-Net Data Coordinating Center (DCC). Separate FOAs have been issued to solicit applications for the Clinical Coordinating Center (RFA-NS-19-023) and Specialized Clinical Centers (RFA-NS-19-025). Clinical trials conducted through EPPIC-Net may come from a variety of sources including the HEAL initiative, as described above, or from separate NIH funding announcements.

Awards for a hub and a Clinical Coordinating Center (CCC, RFA-NS-19-023 ) or Data Coordinating Center (DCC, RFA NS-19-024) may be made to the same institution. There must be different PDs/PIs leading the hub and the CCC or DCC to ensure that each activity receives full attention.

For More Information: See FOA attached.

Limit (Number of applicants permitted per institution): 
1
Sponsor LOI Deadline: 
Jan 06, 2019
Sponsor Final Deadline: 
Feb 06, 2019
OVPR Application or NOI Instructions: 

If you are interested in submitting a proposal, click on the submit application on the right side of page and follow the required prompts to give us your contact information. If interest exceeds the sponsor's institutional limit, the Office of the Vice President for Research will hold an internal Limited Submissions competition after the Call of Intent deadline.

To be considered as a Penn State institutional nominee, please submit a notice of intent by the date provided directly below.
Penn State OVPR NOI Deadline: 
Wednesday, January 2, 2019 - 11:59pm
This limited submission is in downselect: 
Penn State may only submit a specific number of proposals to this funding opportunity. The number of NOIs received require that an internal competition take place, thus, a downselect process has commenced. No Penn State researchers may apply to this opportunity outside of this downselect process. To apply for this limited submission, please use this link:
Notes: 
No applicants