G. Harold and Leila Y. Mathers Charitable Foundation: Spring 2023

Sponsor Name: 
G. Harold and Leila Y. Mathers Charitable Foundation
Description of the Award: 

The mission of The G. Harold and Leila Y. Mathers Foundation is to advance knowledge in the life sciences by sponsoring scientific research that will benefit mankind. The foundation’s grants program seeks to support basic science, ideally with potential translational applications. Immunology, microbiome, genomics, structural biology, cellular physiology, neuroscience, etc., are some noteworthy examples of current research support. PSU may submit up to four letters of intent for each cycle.

For many years the Foundation has enjoyed special recognition in the research community in supporting “basic” scientific research, realizing that true transformative breakthroughs usually occur after a thorough understanding of the fundamental mechanisms underlying natural phenomena. More recently, and with the advent of newer investigative methodologies, technology, and tools, the Foundation now embraces innovative translational research proposals.

Award information

  • The grant duration must be three years
  • Award amount: No specified limit. The budget should be reasonable based on the aims of the project. Indirect costs may not exceed 10%. Preliminary Budgets are required during the LOI phase. A detailed budget justification is not required until the proposal phase. For guidance on an appropriate budget, please contact Jessica Kiely, MEd., Director, Corporate and Foundation Relations
  • The Foundation’s grant award is not intended to be utilized for purchasing capital equipment (“bricks-and-mortar”) for the lab and is intended only to support the actual investigation. The Foundation assumes and expects that capital equipment must be provided by the research institution or university.

Application Guidance

  • The Foundation primarily supports basic science, ideally with potential translational applications.
  • Immunology, microbiome, genomics, structural biology, cellular physiology, neuroscience, etc., are some noteworthy examples of current research support.
  • Covid-19 related research projects (aims or sub-aims) will not be considered for support.
  • Medical imaging technology related projects and/or electrical engineering technology development projects will not be considered for support.
  • Plant Biology Research, Oceanography, Space Exploration. and Global Warming related research will not be considered for support.
  • As technology continues to advance, it is apparent that investigations in the area of basic science and translational research may become more and more reliant on collaborative, interdisciplinary projects. It is important to note that any interdisciplinary project proposals may require additional information regarding collaborator(s)’ achievements and relevant expertise.
  • Feedback for declined LOI Requests will not be provided; LOIs or Formal Proposals that have been declined should not be resubmitted at a later date for consideration.
  • Renewal applications for the same or related research will not be accorded priority consideration. It is strongly advised that any re-application for grant renewal consider a new direction based on prior research or emphasize some new potential translational aspects and not merely an extension of previously funded research.
  • Requests for funding previously federally supported research and/or applications pending federal approval will not be accorded priority consideration.
  • Requests for support of clinical trials or drug discovery will not be approved. The Foundation will not support projects which we consider pre-clinical drug development.
Sponsor LOI Deadline: 
Mar 31, 2023
Sponsor Final Deadline: 
Jun 16, 2023
OSVPR Application or NOI Instructions: 

Interested applicants should upload the following documents in sequence in one PDF file (File name: Last name_Mathers_Spring2023.pdf) no later than 4:00 p.m. on the internal submission deadline:

1. Cover Letter (1 page, pdf):

  • Descriptive title of proposed activity
  • PI name, departmental affiliations(s) and contact information
  • Co-PI's names and departmental affiliation(s)
  • Names of other key personnel
  • Participating institution(s)
  • Number and title of this funding opportunity

2. Project Summary (no more than 7000 characters with spaces, pdf) to include a short summary of the proposed research project.

3. Preliminary Estimated Budget (1 page max.) - Please provide a preliminary budget figure, which should include any indirect/overhead expenses (up to 10% of direct expenses). A detailed budget justification is not required until the proposal phase.

4. Aims of Project (no more than 2000 characters with spaces, pdf)

5. Proof of concept, previous or related work (no more than 2000 characters with spaces, pdf)

6. Brief summary of your most impactful discoveries and/or best publications (no more than 2500 characters with spaces, pdf) - Please provide a brief summary of your most impactful discoveries and/or best publications. The discoveries and papers discussed in this section do not necessarily have to be related to the subject matter of this application.)

7. 2-page CV's of Investigators

Formatting Guidelines:

Font/size: Times New Roman (12 pt.)
Document margins: 1.0” (top, bottom, left and right)
Standard paper size (8 ½” x 11)

To be considered as a Penn State institutional nominee, please submit a notice of intent by the date provided directly below.
OSVPR Downselect Deadline: 
Wednesday, February 15, 2023 - 4:00pm
For help or questions: 

Please plan to connect with staff from the Office of Foundation Relations, who will consult on proposal narrative elements, answer foundation-related questions, and assist the downselect winner with their submission. Applicants please contact Jessica Kiely, Director of Corporate and Foundation Relations, Penn State College of Medicine (jkiely1@pennstatehealth.psu.edu) for additional support.