Investigator Manual

The Investigator Manual is designed to guide researchers through policies and procedures related to the conduct of Human Subject Research that are specific to Penn State.  The link below takes you to a .pdf version of the Manual.  If you would like the Manual in another format, please email us at

Quick Tip: The Investigator Manual is searchable by using the Magnifying Glass or “Ctrl + F” function.  The Table of Contents is hyperlinked to sections in the document. 

Access the Investigator Manual


The pSite Investigator Manual is designed to guide investigators when they are participating as a site on a multi-site or collaborative study.  These are Penn State'e requirements for participating sites.


Access the pSite Investigator Manual